M.S. AAI Capstone Chronicles 2024

indicates a higher rate of overall deterioration in the patient’s condition. Example score calculations for a subset of the features are illustrated in Table 1. Table 1 Feature level scoring examples for rollup into the Deterioration Index

Feature

Normal (0pts)

Moderate Condition (+1pts) 100-120 bpm (mild tachycardia) -or 60-70bpm (mild bradycardia)

Severe Condition (+2pts) >120bpm (severe tachycardia) -or- <60bpm (severe bradycardia)

Heart Rate

70-100bpm

Temperature

36-37.9°C

38–39°C (mild fever) -or 35–35.9°C

>39°C (severe fever) -or- <35°C (hypothermia)

Platelets

≥100x10³μL

50–100 x10³/μL

<50 x10³/μL

Each score was then weighted for clinical importance using the feature importance derived from the DTC and summed into a composite index as seen in Equation (1).

Deterioration Index =∑ (Score i ×Weight i )

(1)

This calculation ensures that features with higher clinical importance, such as temperature, platelets, and WBC, exert a greater influence on the index. Additionally, the scoring system accounts for improvements back to normal ranges, providing a dynamic and clinically meaningful measure of patient stability or decline.

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